What is L. johnsonii No. 1088?

Lactobacillus johnsonii (L. johnsonii) No. 1088 is a breakthrough in the research of Lactic Acid Bacteria. A novel strain of lactic acid bacteria (LAB) discovered in healthy Japanese individuals, it has been extensively studied for its beneficial properties to address the root causes of gastric problems and provide long-lasting soothing and protective effects. L. johnsonii No. 1088 is a natural alternative for recurring gastric symptoms and a long-term solution to help break the cycle of drug dependency. It is a key ingredient of GASTRICELL, an advanced gastro solution developed to address recurring gastric discomfort.

The Healing Properties of L. johnsonii No. 1088

Although gastric acid is important for digestion and also helps to kill harmful bacteria in the stomach, excessive gastric acid production due to factors such as stress and poor diet can sometimes lead to gastric problems like ulcer, acid reflux and heartburn.

Antacids and Proton Pump Inhibitors (PPIs) are the common remedies used to soothe these symptoms of gastric discomforts. However, these medications can only provide temporary relief and are unable to treat the underlying root cause of the problem. Antacids neutralise the gastric acid to provide temporary pain relief while PPIs medication tend to over-suppress gastric acid production, resulting in diverse side effects that include impaired food digestion and nutrient absorption. Users of PPIs whose gastric acid production is suppressed by the drug may lack the required gastric acid to defend against malicious bacteria and become vulnerable to a range of infections such as Clostridium difficile and H. pylori.

Unlike medications, L. johnsonii No. 1088 is a natural ingredient and does not have a negative effect on the digestive system. This Lactic Acid Bacteria (LAB) strain reduces gastrin (a peptide hormone in the stomach that stimulates the secretion of gastric acid) and overactive gastric acid secretion and maintains them at an optimal level for effective digestion and pain relief. L. johnsonii No. 1088 targets the root cause of gastric concerns to provide long-term soothing effects.

L. johnsonii No. 1088 Helps Manage the Side effect of H. pylori Treatment

In addition to gastrin and gastric acid suppression, L. johnsonii No. 1088 is also capable of reducing the number of H. pylori (a major cause of peptic ulcer) and other harmful bacteria, such as Escherichia coli O-157, Salmonella typhimurium and Clostridium difficile.

The eradication of H. pylori bacteria by medications may bring about a possible side effect of gastroesophageal reflux disease (GERD) or acid reflux. Soon after the bacteria had been successfully eliminated, the gastric acid concentration in the stomach would be restored.  In some cases where the patient has weak lower esophageal sphincter (LES) muscles, this may result in a backflow of gastric acid up the oesophagus, a condition known as acid reflux.

L. johnsonii No. 1088 has the unique ability to synergistically eradicate H. pylori and suppress overactive gastric acid secretion (if necessary) to prevent GERD symptoms from arising after the elimination of H. pylori from the body.

Other Benefits of L. johnsonii No. 1088

Besides the beneficial effects on the stomach, L. johnsonii No. 1088 also regulates intestinal flora by helping to increase the number of Bifidobacteria (good bacteria) residing in the intestines. Bifidobacteria promote good digestion, boost immunity, produce lactic and acetic acid to control intestinal pH and inhibit the growth of pathogenic (malicious) bacteria. In addition, L. johnsonii No. 1088 also helps to decrease Clostridia, a group of bacteria that are harmful to health when their numbers outgrow that of the good bacteria.

The Unique Qualities of L. johnsonii No. 1088

  • Unique strain – A novel strain discovered in the gastric juice of healthy individuals, its discovery is a breakthrough in the research of Lactic Acid Bacteria.
  • Resilient, superior acid resistance – L. johnsonii No. 1088 has the strongest acid resistance among several lactobacilli examined, with more than 10% of bacterial cells survived at pH 1.0 after 2 hours.

Lactobacillus johnsonii No. 1088 has superior acid resistance compared to other lactobacilli

Growing bacteria were diluted at a density around 107 CFU/mL in acidic buffer and then incubated at 37oC up to 120 min. Living bacterial counts were conducted at various time points.

Microbiology Open 4, 465-474 (2015)

  • Scientifically proven health benefits.
  • Superior potency in targeting the root cause of gastric concerns.

Lactobacillus johnsonii No. 1088 inhibits gastrin secretion most effectively than other lactobacilli

(Published in patents KR101451188 and US 9243300 B2)

  • Backed by extensive research papers.
  • Patented in Japan, Korea and the United States for strain, function and application (patent numbers: JP4457364, JP5075254, KR101061143, KR101451188, US 9243300 B2).
  • Highly safe. Lactobacillus johnsonii 1088 has been listed in the European Food Safety Authority (EFSA) in accordance with Qualified Presumption of Safety (QPS). The safety is further confirmed by acute toxicity, micronucleus and Ames tests.